About DHEA-Sulfate
DHEA-S (Dehydroepiandrosterone Sulfate) is the most abundant steroid hormone in circulation and serves as the precursor for the body's production of testosterone and estrogen. Levels peak in the mid-20s and decline steadily with age — this decline is one of the most consistent hormonal signatures of biological aging. Low DHEA-S is associated with fatigue, low libido, reduced muscle mass, depression, and impaired immune function; abnormally high levels in women raise concern for adrenal androgen excess.